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Frontiers | BH3 Mimetics for the Treatment of Prostate Cancer | Pharmacology
Frontiers | BH3 Mimetics for the Treatment of Prostate Cancer | Pharmacology

In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive  Myc-driven lymphomas | PNAS
In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas | PNAS

PROTACs are effective in addressing the platelet toxicity associated with  BCL-XL inhibitors
PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

Chemical structure and mode of action of the BH3 mimetic ABT-737 in... |  Download Scientific Diagram
Chemical structure and mode of action of the BH3 mimetic ABT-737 in... | Download Scientific Diagram

ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases  antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]
ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]

Why do BCL-2 inhibitors work and where should we use them in the clinic? |  Cell Death & Differentiation
Why do BCL-2 inhibitors work and where should we use them in the clinic? | Cell Death & Differentiation

Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions  with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2,  Bcl-xL, and Mcl-1 | Molecular and Cellular Biology
Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-xL, and Mcl-1 | Molecular and Cellular Biology

Nutrients | Free Full-Text | Glycycoumarin Sensitizes Liver Cancer Cells to  ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin Axis | HTML
Nutrients | Free Full-Text | Glycycoumarin Sensitizes Liver Cancer Cells to ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin Axis | HTML

Cancers | Free Full-Text | The Application of Arsenic Trioxide in  Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells  through Unique Pathways in Cell Death | HTML
Cancers | Free Full-Text | The Application of Arsenic Trioxide in Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells through Unique Pathways in Cell Death | HTML

The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of  Cancer Cells and Resistance to Antagonist ABT-737* - Journal of Biological  Chemistry
The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737* - Journal of Biological Chemistry

The regulation of MCL-1 by Noxa expression and the mechanisms of... |  Download Scientific Diagram
The regulation of MCL-1 by Noxa expression and the mechanisms of... | Download Scientific Diagram

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT- 737 in acute myeloid leukemia - ScienceDirect
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT- 737 in acute myeloid leukemia - ScienceDirect

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby  increasing drug resistance | EMBO reports
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance | EMBO reports

Genetics and biomarkers in personalisation of lung cancer treatment - The  Lancet
Genetics and biomarkers in personalisation of lung cancer treatment - The Lancet

Repurposing apoptosis-inducing cancer drugs to treat schistosomiasis |  Future Medicinal Chemistry
Repurposing apoptosis-inducing cancer drugs to treat schistosomiasis | Future Medicinal Chemistry

Use of Human Cancer Cell Lines Mitochondria to Explore the Mechanisms of  BH3 Peptides and ABT-737-Induced Mitochondrial Membrane Permeabilization
Use of Human Cancer Cell Lines Mitochondria to Explore the Mechanisms of BH3 Peptides and ABT-737-Induced Mitochondrial Membrane Permeabilization

Inner Mitochondrial Membrane Disruption Links Apoptotic and  Agonist-Initiated Phosphatidylserine Externalization in Platelets |  Arteriosclerosis, Thrombosis, and Vascular Biology
Inner Mitochondrial Membrane Disruption Links Apoptotic and Agonist-Initiated Phosphatidylserine Externalization in Platelets | Arteriosclerosis, Thrombosis, and Vascular Biology

Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to  foresee the complexities of personalized medicine | Journal of Molecular  Signaling | Full Text
Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine | Journal of Molecular Signaling | Full Text

Synergistic Anticancer Effects of the 9.2.27PE Immunotoxin and ABT-737 in  Melanoma
Synergistic Anticancer Effects of the 9.2.27PE Immunotoxin and ABT-737 in Melanoma

Targeting Multiple Arms of the Apoptotic Regulatory Machinery | Cancer  Research
Targeting Multiple Arms of the Apoptotic Regulatory Machinery | Cancer Research

Cancers | Free Full-Text | The Application of Arsenic Trioxide in  Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells  through Unique Pathways in Cell Death | HTML
Cancers | Free Full-Text | The Application of Arsenic Trioxide in Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells through Unique Pathways in Cell Death | HTML

Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review
Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review

ABT-737 - Wikipedia
ABT-737 - Wikipedia

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts -  ScienceDirect
ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts - ScienceDirect

Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to  foresee the complexities of personalized medicine | Journal of Molecular  Signaling | Full Text
Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine | Journal of Molecular Signaling | Full Text

Schematic summary of the effects of ABT-737 on human oral cancer cells....  | Download Scientific Diagram
Schematic summary of the effects of ABT-737 on human oral cancer cells.... | Download Scientific Diagram

Attacking cancer's Achilles heel: antagonism of anti‐apoptotic BCL‐2 family  members - Opferman - 2016 - The FEBS Journal - Wiley Online Library
Attacking cancer's Achilles heel: antagonism of anti‐apoptotic BCL‐2 family members - Opferman - 2016 - The FEBS Journal - Wiley Online Library